SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02962

Signal sequence   MRTLALSLALALLCLLHTEA

Length  20

Organism  Gallus gallus (Chicken)

UniProt ID  P21760,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02962.cif

Structure  SPKB02962.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2153.66954

Aliphatic index  176

Isoelectric point  7.360093818

Charge (pH=7)   0.028690486

Topological polar surface area  804.79

Aromaticity  0

Average rotatable bonds  3.55

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  29

X logP energy  -4.41143

Hydropathy 



Literature Information


Title  The amino terminal sequence of the developmentally regulated Ch21 protein shows homology with amino terminal sequences of low molecular weight proteins binding hydrophobic molecules.

DOI  10.1016/0006-291x(90)91118-c,

Publication Year  1990

PubMed ID  2346493,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.