SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02961

Signal sequence   MELSYRLFICLLLWGSTELCYP

Length  22

Organism  Homo sapiens (Human)

UniProt ID  P21754,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02961.cif

Structure  SPKB02961.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2651.19164

Aliphatic index  124.0909091

Isoelectric point  4.258066725

Charge (pH=7)   -1.124119027

Topological polar surface area  919.07

Aromaticity  0.181818182

Average rotatable bonds  3.727272727

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  34

X logP energy  -2.12633

Hydropathy 



Literature Information


Title  Mass spectrometry analysis of recombinant human ZP3 expressed in glycosylation-deficient CHO cells.

DOI  10.1021/bi048958k,

Publication Year  2004

PubMed ID  15379548,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.