SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02960

Signal sequence   MLPFGLVAALLLAAGPRPSLG

Length  21

Organism  Rattus norvegicus (Rat)

UniProt ID  P21744,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02960.cif

Structure  SPKB02960.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2064.56014

Aliphatic index  144.2857143

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  701.08

Aromaticity  0.047619048

Average rotatable bonds  2.904761905

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  25

X logP energy  -3.22933

Hydropathy 



Literature Information


Title  Identification of a novel binding protein for insulin-like growth factors in adult rat serum.

DOI  10.1016/0006-291x(89)91053-x,

Publication Year  1989

PubMed ID  2480123,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.