SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02952

Signal sequence   MKAFWRNAALLAVSLLPFSSANA

Length  23

Organism  Escherichia coli (strain K12)

UniProt ID  P21338,

Motif  1..23



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02952.cif

Structure  SPKB02952.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2478.93774

Aliphatic index  106.5217391

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  945.31

Aromaticity  0.130434783

Average rotatable bonds  3.347826087

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  32

X logP energy  -7.38763

Hydropathy 



Literature Information


Title  Cloning and sequencing the gene encoding Escherichia coli ribonuclease I: exact physical mapping using the genome library.

DOI  10.1016/0378-1119(90)90406-h,

Publication Year  1990

PubMed ID  2253883,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.