SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02951

Signal sequence   MQAQQYQQQRRKFAAAFLAFIFILAAVDTAEA

Length  32

Organism  Homo sapiens (Human)

UniProt ID  P21246,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02951.cif

Structure  SPKB02951.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3647.21214

Aliphatic index  85.9375

Isoelectric point  9.296419389

Charge (pH=7)   0.999053836

Topological polar surface area  1488.84

Aromaticity  0.15625

Average rotatable bonds  3.78125

Number of hydrogen bond donors  50

Number of hydrogen bond acceptors  47

X logP energy  -11.91236

Hydropathy 



Literature Information


Title  A heparin-binding growth factor secreted from breast cancer cells homologous to a developmentally regulated cytokine.

DOI  NA,

Publication Year  1992

PubMed ID  1733956,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.