General Information
SPKB ID SPKB02948
Signal sequence MRACISLVLAVLCGLAWA
Length 18
Organism Homo sapiens (Human)
UniProt ID P21128,
Motif 1..18
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 9FTW,
Predicted Structure ID SPKB02948.cif
Physicochemical Information
Molecular weight 1890.39364
Aliphatic index 162.7777778
Isoelectric point 8.231408964
Charge (pH=7) 0.874031556
Topological polar surface area 655.94
Aromaticity 0.055555556
Average rotatable bonds 3.277777778
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 24
X logP energy -2.51433
Hydropathy
Literature Information
Title Cloning and expression of a cDNA encoding human placental protein 11, a putative serine protease with diagnostic significance as a tumor marker.
Publication Year 1990
PubMed ID 2350438,
Patent ID NA,