SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02947

Signal sequence   MLRARPALWAAALTALTLLRGPPAARA

Length  27

Organism  Bos taurus (Bovine)

UniProt ID  P20959,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02947.cif

Structure  SPKB02947.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2829.44884

Aliphatic index  120

Isoelectric point  12.97714556

Charge (pH=7)   3.997971054

Topological polar surface area  1097.4

Aromaticity  0.037037037

Average rotatable bonds  3.148148148

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  35

X logP energy  -8.09942

Hydropathy 



Literature Information


Title  Structural and biological characterization of bovine insulin-like growth factor binding protein-3.

DOI  10.1210/endo-127-6-2795,

Publication Year  1990

PubMed ID  1701128,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.