General Information
SPKB ID SPKB02946
Signal sequence MARKSNLPVLLVPFLLCQALVRC
Length 23
Organism Homo sapiens (Human)
UniProt ID P20933,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02946.cif
Physicochemical Information
Molecular weight 2585.26904
Aliphatic index 148.2608696
Isoelectric point 9.914555929
Charge (pH=7) 2.873733211
Topological polar surface area 942.17
Aromaticity 0.043478261
Average rotatable bonds 3.608695652
Number of hydrogen bond donors 34
Number of hydrogen bond acceptors 33
X logP energy -4.99516
Hydropathy
Literature Information
Title Aspartylglycosaminuria in the Finnish population: identification of two point mutations in the heavy chain of glycoasparaginase.
Publication Year 1991
PubMed ID 2011603,
Patent ID NA,