General Information
SPKB ID SPKB02945
Signal sequence MEFLWAPLLGLCCSLAAA
Length 18
Organism Homo sapiens (Human)
UniProt ID P20827,
Motif 1..18
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02945.cif
Physicochemical Information
Molecular weight 1909.34974
Aliphatic index 130.5555556
Isoelectric point 3.849941048
Charge (pH=7) -1.12419001
Topological polar surface area 622.55
Aromaticity 0.111111111
Average rotatable bonds 3.166666667
Number of hydrogen bond donors 23
Number of hydrogen bond acceptors 24
X logP energy -1.4759
Hydropathy
Literature Information
Title Signal peptide prediction based on analysis of experimentally verified cleavage sites.
DOI 10.1110/ps.04682504,
Publication Year 2004
PubMed ID 15340161,
Patent ID NA,