SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02944

Signal sequence   MKKTQTWIITCIYLQLLLFNPLVKT

Length  25

Organism  Mus musculus (Mouse)

UniProt ID  P20826,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02944.cif

Structure  SPKB02944.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3009.74484

Aliphatic index  136.4

Isoelectric point  10.13347695

Charge (pH=7)   2.934274068

Topological polar surface area  1077.2

Aromaticity  0.12

Average rotatable bonds  3.96

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  39

X logP energy  -3.521

Hydropathy 



Literature Information


Title  Identification of a ligand for the c-kit proto-oncogene.

DOI  10.1016/0092-8674(90)90297-r,

Publication Year  1990

PubMed ID  1698553,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.