SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02934

Signal sequence   MTRLTVLALLAGLLASSRA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P20160,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02934.cif

Structure  SPKB02934.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1957.40554

Aliphatic index  159.4736842

Isoelectric point  12.50010931

Charge (pH=7)   1.997977677

Topological polar surface area  791.84

Aromaticity  0

Average rotatable bonds  3.421052632

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  27

X logP energy  -7.20586

Hydropathy 



Literature Information


Title  Characterization of the biosynthesis, processing, and sorting of human HBP/CAP37/azurocidin.

DOI  10.1002/jlb.66.4.634,

Publication Year  1999

PubMed ID  10534120,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.