General Information
SPKB ID SPKB02933
Signal sequence MALSVLRLALLLLAVTFAASLIP
Length 23
Organism Homo sapiens (Human)
UniProt ID P20155,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02933.cif
Physicochemical Information
Molecular weight 2397.04394
Aliphatic index 199.5652174
Isoelectric point 10.55000222
Charge (pH=7) 0.997980988
Topological polar surface area 817.32
Aromaticity 0.043478261
Average rotatable bonds 3.304347826
Number of hydrogen bond donors 29
Number of hydrogen bond acceptors 29
X logP energy -1.97903
Hydropathy 
Literature Information
Title Amino acid sequence elucidation of human acrosin-trypsin inhibitor (HUSI-II) reveals that Kazal-type proteinase inhibitors are structurally related to beta-subunits of glycoprotein hormones.
DOI 10.1016/0014-5793(90)81273-q,
Publication Year 1990
PubMed ID 2226783,
Patent ID NA,
