General Information
SPKB ID SPKB02932
Signal sequence MKWMVVVLVCLQLLEA
Length 16
Organism Homo sapiens (Human)
UniProt ID P20142,
Motif 1..16
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02932.cif
Physicochemical Information
Molecular weight 1875.41954
Aliphatic index 176.25
Isoelectric point 6.231833229
Charge (pH=7) -0.062510328
Topological polar surface area 622.02
Aromaticity 0.0625
Average rotatable bonds 3.875
Number of hydrogen bond donors 22
Number of hydrogen bond acceptors 23
X logP energy 0.9179
Hydropathy
Literature Information
Title A comparative study on the NH2-terminal amino acid sequences and some other properties of six isozymic forms of human pepsinogens and pepsins.
DOI 10.1093/oxfordjournals.jbchem.a122952,
Publication Year 1989
PubMed ID 2515193,
Patent ID NA,