SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02931

Signal sequence   MIGMNLQLVCLTLLAFSSWSLC

Length  22

Organism  Rattus norvegicus (Rat)

UniProt ID  P20068,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02931.cif

Structure  SPKB02931.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2444.02114

Aliphatic index  141.8181818

Isoelectric point  5.826007312

Charge (pH=7)   -0.125965132

Topological polar surface area  857.31

Aromaticity  0.090909091

Average rotatable bonds  3.590909091

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  33

X logP energy  -4.9598

Hydropathy 



Literature Information


Title  Immunological and biochemical characterization of processing products from the neurotensin/neuromedin N precursor in the rat medullary thyroid carcinoma 6-23 cell line.

DOI  10.1042/bj2910225,

Publication Year  1993

PubMed ID  8471039,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.