SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02927

Signal sequence   MLLLPLLVLLCVVSVSS

Length  17

Organism  Rattus norvegicus (Rat)

UniProt ID  P19999,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02927.cif

Structure  SPKB02927.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1799.34414

Aliphatic index  228.8235294

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  580.82

Aromaticity  0

Average rotatable bonds  3.352941176

Number of hydrogen bond donors  21

Number of hydrogen bond acceptors  23

X logP energy  -0.7322

Hydropathy 



Literature Information


Title  Serum lectin with known structure activates complement through the classical pathway.

DOI  NA,

Publication Year  1987

PubMed ID  3584121,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.