General Information
SPKB ID SPKB02926
Signal sequence MRASSFLIVVVFLIAGTLVLEA
Length 22
Organism Homo sapiens (Human)
UniProt ID P19957,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02926.cif
Physicochemical Information
Molecular weight 2349.90064
Aliphatic index 172.7272727
Isoelectric point 6.410149741
Charge (pH=7) -0.000243889
Topological polar surface area 834.31
Aromaticity 0.090909091
Average rotatable bonds 3.454545455
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 29
X logP energy -3.09723
Hydropathy
Literature Information
Title SKALP/elafin: an elastase inhibitor from cultured human keratinocytes. Purification, cDNA sequence, and evidence for transglutaminase cross-linking.
DOI NA,
Publication Year 1993
PubMed ID 7685029,
Patent ID NA,