General Information
SPKB ID SPKB02922
Signal sequence MNSKLAVALLATFLLSLTLCEA
Length 22
Organism Oryctolagus cuniculus (Rabbit)
UniProt ID P19874,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02922.cif
Physicochemical Information
Molecular weight 2322.84684
Aliphatic index 155.4545455
Isoelectric point 6.231833229
Charge (pH=7) -0.062510328
Topological polar surface area 861.75
Aromaticity 0.045454545
Average rotatable bonds 3.5
Number of hydrogen bond donors 31
Number of hydrogen bond acceptors 32
X logP energy -5.8216
Hydropathy
Literature Information
Title A novel neutrophil chemoattractant generated during an inflammatory reaction in the rabbit peritoneal cavity in vivo. Purification, partial amino acid sequence and structural relationship to interleukin 8.
DOI 10.1042/bj2710797,
Publication Year 1990
PubMed ID 2244880,
Patent ID NA,