SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02921

Signal sequence   MGRLQLVVLGLTCCWAVASA

Length  20

Organism  Homo sapiens (Human)

UniProt ID  P19835,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02921.cif

Structure  SPKB02921.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2091.57574

Aliphatic index  136.5

Isoelectric point  8.231408964

Charge (pH=7)   0.874031556

Topological polar surface area  777.46

Aromaticity  0.05

Average rotatable bonds  3.3

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  28

X logP energy  -5.67703

Hydropathy 



Literature Information


Title  Structure of human milk bile salt activated lipase.

DOI  10.1021/bi00216a028,

Publication Year  1991

PubMed ID  1988041,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.