SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02920

Signal sequence   MPALGWAVAAILMLQTAMA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P19801,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02920.cif

Structure  SPKB02920.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1959.45364

Aliphatic index  128.9473684

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  657.44

Aromaticity  0.052631579

Average rotatable bonds  3.157894737

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  25

X logP energy  -2.1483

Hydropathy 



Literature Information


Title  Diamine oxidase is the amiloride-binding protein and is inhibited by amiloride analogues.

DOI  NA,

Publication Year  1994

PubMed ID  8144586,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.