SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02917

Signal sequence   MGLSTVPDLLLPLVLLELLVGIYPSGVIG

Length  29

Organism  Homo sapiens (Human)

UniProt ID  P19438,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02917.cif

Structure  SPKB02917.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2992.69094

Aliphatic index  187.9310345

Isoelectric point  3.550073361

Charge (pH=7)   -2.000644508

Topological polar surface area  1007.27

Aromaticity  0.034482759

Average rotatable bonds  3.206896552

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  37

X logP energy  -2.4457

Hydropathy 



Literature Information


Title  Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor.

DOI  10.1016/0092-8674(90)90815-v,

Publication Year  1990

PubMed ID  2158862,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.