SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02914

Signal sequence   MRSLLLGTLCLLAVALA

Length  17

Organism  Mus musculus (Mouse)

UniProt ID  P19324,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02914.cif

Structure  SPKB02914.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1758.25414

Aliphatic index  195.2941176

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  631.28

Aromaticity  0

Average rotatable bonds  3.411764706

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  23

X logP energy  -2.85583

Hydropathy 



Literature Information


Title  Molecular cloning of a mouse 47-kDa heat-shock protein (HSP47), a collagen-binding stress protein, and its expression during the differentiation of F9 teratocarcinoma cells.

DOI  10.1111/j.1432-1033.1992.tb16930.x,

Publication Year  1992

PubMed ID  1317794,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.