SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02911

Signal sequence   MRGSGTGAALLVLLASVLWVTVRS

Length  24

Organism  Mus musculus (Mouse)

UniProt ID  P19137,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02911.cif

Structure  SPKB02911.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2457.96034

Aliphatic index  142.0833333

Isoelectric point  12.50010931

Charge (pH=7)   1.997977677

Topological polar surface area  973.36

Aromaticity  0.041666667

Average rotatable bonds  3.291666667

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  33

X logP energy  -8.90076

Hydropathy 



Literature Information


Title  Complete sequence, recombinant analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin alpha3B and alpha5 chains.

DOI  10.1042/0264-6021:3620213,

Publication Year  2002

PubMed ID  11829758,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.