SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02904

Signal sequence   MGTRFLLALCLVLLVLGFEVQG

Length  22

Organism  Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

UniProt ID  P18658,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02904.cif

Structure  SPKB02904.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2392.98674

Aliphatic index  168.1818182

Isoelectric point  6.232433001

Charge (pH=7)   -0.062218605

Topological polar surface area  836.94

Aromaticity  0.090909091

Average rotatable bonds  3.590909091

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  29

X logP energy  -2.27343

Hydropathy 



Literature Information


Title  Homologues of the human C and A apolipoproteins in the Macaca fascicularis (cynomolgus) monkey.

DOI  10.1021/bi00379a037,

Publication Year  1987

PubMed ID  3105581,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.