General Information
SPKB ID SPKB02900
Signal sequence MEICRGLRSHLITLLLFLFHSETIC
Length 25
Organism Homo sapiens (Human)
UniProt ID P18510,
Motif 1..25
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02900.cif
Physicochemical Information
Molecular weight 2946.57994
Aliphatic index 140.4
Isoelectric point 7.420204428
Charge (pH=7) 0.059396672
Topological polar surface area 1098.4
Aromaticity 0.08
Average rotatable bonds 3.92
Number of hydrogen bond donors 42
Number of hydrogen bond acceptors 39
X logP energy -5.88816
Hydropathy 
Literature Information
Title Interleukin-1 receptor antagonist activity of a human interleukin-1 inhibitor.
DOI 10.1038/343336a0,
Publication Year 1990
PubMed ID 2137200,
Patent ID NA,
