SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02899

Signal sequence   MGALARALPSILLALLLTSTPEALG

Length  25

Organism  Homo sapiens (Human)

UniProt ID  P18428,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02899.cif

Structure  SPKB02899.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2493.04324

Aliphatic index  160.4

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  924.26

Aromaticity  0

Average rotatable bonds  3.16

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  33

X logP energy  -6.54953

Hydropathy 



Literature Information


Title  Structure and function of lipopolysaccharide binding protein.

DOI  10.1126/science.2402637,

Publication Year  1990

PubMed ID  2402637,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.