SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02895

Signal sequence   MCFIKQGWCLVLELLLLPLGTG

Length  22

Organism  Mus musculus (Mouse)

UniProt ID  P18181,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02895.cif

Structure  SPKB02895.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2448.08084

Aliphatic index  155

Isoelectric point  6.13535235

Charge (pH=7)   -0.124485044

Topological polar surface area  808.06

Aromaticity  0.090909091

Average rotatable bonds  3.590909091

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  30

X logP energy  -0.7762

Hydropathy 



Literature Information


Title  CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation.

DOI  10.1084/jem.176.5.1241,

Publication Year  1992

PubMed ID  1383383,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.