SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02889

Signal sequence   MNHLVMISLALLLLLGVES

Length  19

Organism  Leiurus hebraeus (Hebrew deathstalker scorpion) (Leiurus quinquestriatus hebraeus)

UniProt ID  P17728,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02889.cif

Structure  SPKB02889.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2066.58834

Aliphatic index  200

Isoelectric point  5.363507222

Charge (pH=7)   -0.909331487

Topological polar surface area  736.65

Aromaticity  0

Average rotatable bonds  3.684210526

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  27

X logP energy  -2.3464

Hydropathy 



Literature Information


Title  A scorpion venom neurotoxin paralytic to insects that affects sodium current inactivation: purification, primary structure, and mode of action.

DOI  10.1021/bi00477a009,

Publication Year  1990

PubMed ID  2383565,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.