SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02888

Signal sequence   MAPWMHLLTVLALLALWGPNSVQA

Length  24

Organism  Octodon degus (Degu) (Sciurus degus)

UniProt ID  P17715,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02888.cif

Structure  SPKB02888.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2633.20784

Aliphatic index  138.3333333

Isoelectric point  7.550323994

Charge (pH=7)   0.08889339

Topological polar surface area  901.94

Aromaticity  0.083333333

Average rotatable bonds  3.25

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  32

X logP energy  -2.7053

Hydropathy 



Literature Information


Title  Amino acid sequence from degu islet amyloid-derived insulin shows unique sequence characteristics.

DOI  10.1016/0006-291x(90)90369-x,

Publication Year  1990

PubMed ID  2192710,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.