SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02887

Signal sequence   MKTLLLLMGLLLSWESGWA

Length  19

Organism  Bos taurus (Bovine)

UniProt ID  P17697,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02887.cif

Structure  SPKB02887.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2162.67634

Aliphatic index  148.9473684

Isoelectric point  6.408795646

Charge (pH=7)   -0.000535612

Topological polar surface area  742.71

Aromaticity  0.105263158

Average rotatable bonds  3.736842105

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  27

X logP energy  -0.9565

Hydropathy 



Literature Information


Title  The primary structure of glycoprotein III from bovine adrenal medullary chromaffin granules. Sequence similarity with human serum protein-40,40 and rat Sertoli cell glycoprotein.

DOI  NA,

Publication Year  1990

PubMed ID  1691174,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.