SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02886

Signal sequence   MAPSISRGLLLLAALCCLAPSFLA

Length  24

Organism  Rattus norvegicus (Rat)

UniProt ID  P17475,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02886.cif

Structure  SPKB02886.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2432.03864

Aliphatic index  150.8333333

Isoelectric point  8.231408964

Charge (pH=7)   0.874031556

Topological polar surface area  837.63

Aromaticity  0.041666667

Average rotatable bonds  3.125

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -5.24363

Hydropathy 



Literature Information


Title  Molecular cloning and primary structure of rat alpha 1-antitrypsin.

DOI  10.1021/bi00454a004,

Publication Year  1990

PubMed ID  2302382,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.