SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02885

Signal sequence   MGTWARALLGSTLLSLLLAAAPGALG

Length  26

Organism  Oryctolagus cuniculus (Rabbit)

UniProt ID  P17454,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02885.cif

Structure  SPKB02885.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2525.04744

Aliphatic index  143.0769231

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  940.64

Aromaticity  0.038461538

Average rotatable bonds  3.038461538

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  33

X logP energy  -7.47513

Hydropathy 



Literature Information


Title  Isolation of a lipopolysaccharide-binding acute phase reactant from rabbit serum.

DOI  10.1084/jem.164.3.777,

Publication Year  1986

PubMed ID  2427635,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.