SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02883

Signal sequence   MRENMARGPCNAPRWASLMVLVAIGTAVTAA

Length  31

Organism  Homo sapiens (Human)

UniProt ID  P17213,

Motif  1..31



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02883.cif

Structure  SPKB02883.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3258.88384

Aliphatic index  88.38709677

Isoelectric point  10.43741668

Charge (pH=7)   1.937774772

Topological polar surface area  1304.4

Aromaticity  0.032258065

Average rotatable bonds  3.290322581

Number of hydrogen bond donors  47

Number of hydrogen bond acceptors  45

X logP energy  -13.46449

Hydropathy 



Literature Information


Title  Comparison of granule proteins from human polymorphonuclear leukocytes which are bactericidal toward Pseudomonas aeruginosa.

DOI  10.1128/iai.59.11.4193-4200.1991,

Publication Year  1991

PubMed ID  1937776,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.