SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02881

Signal sequence   MLLKTVLLLGHVAQVLM

Length  17

Organism  Homo sapiens (Human)

UniProt ID  P17050,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02881.cif

Structure  SPKB02881.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1879.43634

Aliphatic index  194.7058824

Isoelectric point  9.702001779

Charge (pH=7)   1.088598356

Topological polar surface area  646.94

Aromaticity  0

Average rotatable bonds  3.764705882

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  24

X logP energy  -0.7017

Hydropathy 



Literature Information


Title  Photolabeling of the alpha-neuraminidase/beta-galactosidase complex from human placenta with a photoreactive neuraminidase inhibitor.

DOI  10.1016/s0006-291x(05)81014-9,

Publication Year  1990

PubMed ID  2256909,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.