SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02880

Signal sequence   MRLLSPVTGSKLVLLFLFLGAVRSDA

Length  26

Organism  Rattus norvegicus (Rat)

UniProt ID  P17046,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02880.cif

Structure  SPKB02880.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2804.43014

Aliphatic index  146.1538462

Isoelectric point  11.47969964

Charge (pH=7)   1.998129127

Topological polar surface area  1050.07

Aromaticity  0.076923077

Average rotatable bonds  3.538461538

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  36

X logP energy  -6.65576

Hydropathy 



Literature Information


Title  Purification, some properties, and tissue distribution of a major lysosome-associated membrane glycoprotein (r-lamp-2) of rat liver.

DOI  10.1093/oxfordjournals.jbchem.a123690,

Publication Year  1991

PubMed ID  1794981,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.