SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02879

Signal sequence   MRAWIFFLLCLAGRALA

Length  17

Organism  Rattus norvegicus (Rat)

UniProt ID  P16975,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  9KAS,

Predicted Structure ID  SPKB02879.cif

Structure  SPKB02879.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1952.45214

Aliphatic index  138.2352941

Isoelectric point  10.52640717

Charge (pH=7)   1.936002961

Topological polar surface area  668.51

Aromaticity  0.176470588

Average rotatable bonds  3.588235294

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  22

X logP energy  -0.48456

Hydropathy 



Literature Information


Title  Purification of a calcium binding protein (rat SPARC) from primary Sertoli cell-enriched culture medium.

DOI  10.1016/0006-291x(90)90677-f,

Publication Year  1990

PubMed ID  2322281,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.