General Information
SPKB ID SPKB02879
Signal sequence MRAWIFFLLCLAGRALA
Length 17
Organism Rattus norvegicus (Rat)
UniProt ID P16975,
Motif 1..17
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 9KAS,
Predicted Structure ID SPKB02879.cif
Physicochemical Information
Molecular weight 1952.45214
Aliphatic index 138.2352941
Isoelectric point 10.52640717
Charge (pH=7) 1.936002961
Topological polar surface area 668.51
Aromaticity 0.176470588
Average rotatable bonds 3.588235294
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 22
X logP energy -0.48456
Hydropathy
Literature Information
Title Purification of a calcium binding protein (rat SPARC) from primary Sertoli cell-enriched culture medium.
DOI 10.1016/0006-291x(90)90677-f,
Publication Year 1990
PubMed ID 2322281,
Patent ID NA,