SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02877

Signal sequence   MLSTQFNRDNQYQAITKPSLLAGCIALALLPSAAFA

Length  36

Organism  Escherichia coli (strain K12)

UniProt ID  P16869,

Motif  1..36



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02877.cif

Structure  SPKB02877.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3839.48264

Aliphatic index  106.1111111

Isoelectric point  8.522871991

Charge (pH=7)   0.935307308

Topological polar surface area  1526.29

Aromaticity  0.083333333

Average rotatable bonds  3.416666667

Number of hydrogen bond donors  52

Number of hydrogen bond acceptors  53

X logP energy  -15.21243

Hydropathy 



Literature Information


Title  Ferric-coprogen receptor FhuE of Escherichia coli: processing and sequence common to all TonB-dependent outer membrane receptor proteins.

DOI  10.1128/jb.169.5.2044-2049.1987,

Publication Year  1987

PubMed ID  3032906,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.