SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02876

Signal sequence   MDPQTAPSRALLLLLFLHLAFLGGRS

Length  26

Organism  Homo sapiens (Human)

UniProt ID  P16860,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02876.cif

Structure  SPKB02876.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2838.40674

Aliphatic index  131.5384615

Isoelectric point  10.39953455

Charge (pH=7)   1.089333252

Topological polar surface area  1066.8

Aromaticity  0.076923077

Average rotatable bonds  3.461538462

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  36

X logP energy  -6.94156

Hydropathy 



Literature Information


Title  Isolation and identification of human brain natriuretic peptides in cardiac atrium.

DOI  10.1016/0006-291x(90)92081-a,

Publication Year  1990

PubMed ID  2138890,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.