SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02871

Signal sequence   MGRLCTKFLTSVGCLILLLVTGSGS

Length  25

Organism  Mus musculus (Mouse)

UniProt ID  P16382,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02871.cif

Structure  SPKB02871.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2570.16214

Aliphatic index  132.4

Isoelectric point  8.828181491

Charge (pH=7)   1.873736522

Topological polar surface area  971.02

Aromaticity  0.04

Average rotatable bonds  3.44

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  37

X logP energy  -9.43923

Hydropathy 



Literature Information


Title  The murine interleukin-4 receptor: molecular cloning and characterization of secreted and membrane bound forms.

DOI  10.1016/0092-8674(89)90295-x,

Publication Year  1989

PubMed ID  2805066,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.