SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02870

Signal sequence   MGAAARSLPLAFCLLLLGTLLPRADA

Length  26

Organism  Bos taurus (Bovine)

UniProt ID  P16368,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02870.cif

Structure  SPKB02870.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2655.25534

Aliphatic index  143.0769231

Isoelectric point  8.54983383

Charge (pH=7)   0.936449445

Topological polar surface area  974.8

Aromaticity  0.038461538

Average rotatable bonds  3.192307692

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  34

X logP energy  -6.41836

Hydropathy 



Literature Information


Title  Purification and characterization of two related but distinct metalloproteinase inhibitors secreted by bovine aortic endothelial cells.

DOI  NA,

Publication Year  1989

PubMed ID  2551903,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.