SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02868

Signal sequence   MGRRVPALRQLLVLAVLLLKPSQLQS

Length  26

Organism  Rattus norvegicus (Rat)

UniProt ID  P16235,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02868.cif

Structure  SPKB02868.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2900.60884

Aliphatic index  161.1538462

Isoelectric point  12.80742779

Charge (pH=7)   3.997679332

Topological polar surface area  1154.69

Aromaticity  0

Average rotatable bonds  3.769230769

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  37

X logP energy  -8.00829

Hydropathy 



Literature Information


Title  Characterization and structure of ovarian and testicular LH/hCG receptors.

DOI  10.1016/0022-4731(89)90482-2,

Publication Year  1989

PubMed ID  2601325,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.