SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02867

Signal sequence   MRSRSFLVLVAVFLICETLVA

Length  21

Organism  Sus scrofa (Pig)

UniProt ID  P16225,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02867.cif

Structure  SPKB02867.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2367.93684

Aliphatic index  157.6190476

Isoelectric point  8.549845238

Charge (pH=7)   0.937778084

Topological polar surface area  867.11

Aromaticity  0.095238095

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  30

X logP energy  -4.08636

Hydropathy 



Literature Information


Title  Cloning, characterization, and tissue distribution of porcine SPAI, a protein with a transglutaminase substrate domain and the WAP motif.

DOI  10.1074/jbc.270.38.22428,

Publication Year  1995

PubMed ID  7673229,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.