SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02865

Signal sequence   MAGPRPSPWARLLLAALISVSLSGTLA

Length  27

Organism  Homo sapiens (Human)

UniProt ID  P16144,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02865.cif

Structure  SPKB02865.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2749.31024

Aliphatic index  130.3703704

Isoelectric point  12.50010931

Charge (pH=7)   1.997977677

Topological polar surface area  1034.29

Aromaticity  0.037037037

Average rotatable bonds  3.074074074

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  36

X logP energy  -8.78366

Hydropathy 



Literature Information


Title  A novel integrin (alpha E beta 4) from human epithelial cells suggests a fourth family of integrin adhesion receptors.

DOI  10.1002/j.1460-2075.1989.tb03425.x,

Publication Year  1989

PubMed ID  2542022,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.