SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02860

Signal sequence   MRKKQKLPFDKLAIALMSTSILLNAQSDIKA

Length  31

Organism  Streptococcus pyogenes

UniProt ID  P15926,

Motif  1..31



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell wall

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02860.cif

Structure  SPKB02860.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3474.22424

Aliphatic index  113.5483871

Isoelectric point  10.96734226

Charge (pH=7)   3.997398787

Topological polar surface area  1404.32

Aromaticity  0.032258065

Average rotatable bonds  4

Number of hydrogen bond donors  48

Number of hydrogen bond acceptors  49

X logP energy  -11.73243

Hydropathy 



Literature Information


Title  Complete nucleotide sequence of the streptococcal C5a peptidase gene of Streptococcus pyogenes.

DOI  NA,

Publication Year  1990

PubMed ID  2406246,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.