SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02856

Signal sequence   MRFSTTLATAATALFFTASQVSA

Length  23

Organism  Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

UniProt ID  P15703,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02856.cif

Structure  SPKB02856.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2393.74014

Aliphatic index  72.60869565

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  970.35

Aromaticity  0.130434783

Average rotatable bonds  3.217391304

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  35

X logP energy  -12.17763

Hydropathy 



Literature Information


Title  Protein expression during exponential growth in 0.7 M NaCl medium of Saccharomyces cerevisiae.

DOI  10.1111/j.1574-6968.1996.tb08073.x,

Publication Year  1996

PubMed ID  8935650,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.