SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02855

Signal sequence   MQGDWVLLLLLGLRIHLSFG

Length  20

Organism  Rattus norvegicus (Rat)

UniProt ID  P15693,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02855.cif

Structure  SPKB02855.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2281.78724

Aliphatic index  170.5

Isoelectric point  7.550936504

Charge (pH=7)   0.089336563

Topological polar surface area  823.21

Aromaticity  0.1

Average rotatable bonds  3.75

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  27

X logP energy  -1.79013

Hydropathy 



Literature Information


Title  Molecular cloning and expression of a cDNA encoding the membrane-associated rat intestinal alkaline phosphatase.

DOI  10.1016/0167-4838(90)90164-b,

Publication Year  1990

PubMed ID  2155025,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.