SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02854

Signal sequence   MNFLLSWVHWSLALLLYLHHAKWSQA

Length  26

Organism  Bos taurus (Bovine)

UniProt ID  P15691,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02854.cif

Structure  SPKB02854.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3165.75134

Aliphatic index  127.6923077

Isoelectric point  9.305406121

Charge (pH=7)   1.269566124

Topological polar surface area  1117.35

Aromaticity  0.192307692

Average rotatable bonds  3.730769231

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  38

X logP energy  -2.183

Hydropathy 



Literature Information


Title  Vascular endothelial growth factor is a secreted angiogenic mitogen.

DOI  10.1126/science.2479986,

Publication Year  1989

PubMed ID  2479986,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.