SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02853

Signal sequence   MLWPCLLALLLSQLNFLCA

Length  19

Organism  Rattus norvegicus (Rat)

UniProt ID  P15589,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02853.cif

Structure  SPKB02853.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2162.73744

Aliphatic index  174.7368421

Isoelectric point  5.826007312

Charge (pH=7)   -0.125965132

Topological polar surface area  700.53

Aromaticity  0.105263158

Average rotatable bonds  3.526315789

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  -0.2479

Hydropathy 



Literature Information


Title  Characterization of rat and human steroid sulfatases.

DOI  10.1016/0167-4838(89)90187-8,

Publication Year  1989

PubMed ID  2765556,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.