SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02852

Signal sequence   MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDA

Length  34

Organism  Homo sapiens (Human)

UniProt ID  P15529,

Motif  1..34



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8QK3,

Predicted Structure ID  SPKB02852.cif

Structure  SPKB02852.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3868.58764

Aliphatic index  86.17647059

Isoelectric point  6.405348973

Charge (pH=7)   -0.060854035

Topological polar surface area  1373.98

Aromaticity  0.147058824

Average rotatable bonds  3.382352941

Number of hydrogen bond donors  48

Number of hydrogen bond acceptors  48

X logP energy  -7.00979

Hydropathy 



Literature Information


Title  Homology of an acrosome-reacted sperm-specific antigen to CD46.

DOI  10.1248/bpb1978.15.455,

Publication Year  1992

PubMed ID  1479546,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.