SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02850

Signal sequence   MKFFVFALVLALMISMISA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P15515,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02850.cif

Structure  SPKB02850.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2132.75194

Aliphatic index  148.9473684

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  653.6

Aromaticity  0.157894737

Average rotatable bonds  3.684210526

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  26

X logP energy  0.8279

Hydropathy 



Literature Information


Title  Rapid purification and characterization of histatins (histidine-rich polypeptides) from human whole saliva.

DOI  10.1016/0003-9969(90)90202-l,

Publication Year  1990

PubMed ID  2372245,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.