SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02849

Signal sequence   MKAVVLTLAVLFLTGSQA

Length  18

Organism  Bos taurus (Bovine)

UniProt ID  P15497,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02849.cif

Structure  SPKB02849.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1862.30134

Aliphatic index  151.6666667

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  687.82

Aromaticity  0.055555556

Average rotatable bonds  3.388888889

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  -4.3724

Hydropathy 



Literature Information


Title  Plasma lipid transport in the preruminant calf, Bos spp: primary structure of bovine apolipoprotein A-I.

DOI  10.1016/0005-2760(92)90104-4,

Publication Year  1992

PubMed ID  1739745,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.